What are the hyaluronic acid Biorevitalization + Glycerol products?

Being a negatively charged polyanionic polymer at physiological pH, the hyaluronic acid has a strong affinity for water, allowing hydration. One gram of hyaluronic acid can bind up to 6 liters of water, and this binding occurs through the formation of a hydrogen bridge with the carboxyl group of the hyaluronic acid molecule.
Hyaluronic acid biorevitalization products are widely used for soft tissue augmentation and facial rejuvenation, as well in reconstructive procedures, addressing age-associated skin laxity or disease-triggered facial asymmetries, contours and irregularities. They are optimal for repairing small to medium sized wrinkles and defects resulting from age-related changes from in dermal/subdermal musculature interactions within the skin.
The most widely used process utilizes fermentation of non-pathogenic Streptococcus bacterial strains that, due to not having antigenic specificity, have a low risk of causing allergic or immune reactions.
Being a water-soluble polymer, hyaluronic acid is quickly eliminated when injected into normal skin.

Radiant non-cross linked hyaluronic acid + Glycerol for biorevitalization

The Non-Cross Linked Hyaluronic Acid + Glycerol is a sterile injectable, pyrogen-free gel, which is composed of a hyaluronic acid from a non-animal origin in a saline solution. The gel is latex free, viscoelastic, clear, colorless and biodegradable.
Radiant Boost is a sterile injectable, pyrogen-free gel, which is composed of a hyaluronic acid from a non-animal origin, dispersed in a saline solution. The gel is latex free, viscoelastic, clear, colorless and biodegradable.
Note: Glycerin is a skin- replenisher and restorer, meaning it is a substance found naturally in the skin. In that respect it is one of the many substances in the skin that help maintain a healthy look and feel, fighting against dryness.

Radiant Biorevitalization + Glycerol

Radiant Boost

  • 18 mg/ml + Glycerol

Radiant Boost ( 18 mg/ml + Glycerol) is provided to the user in 1,0 ml syringes, as shown below:

Illustration Name Composition Concentration Volume Indication Depth
Radiant
Boost
Sodium hyaluronate, 0.9% sodium chloride solution, glycerol 20 mg/ml 18 mg/ml 1,0 ml For superficial lines, fine to moderate wrinkles and minor skin damages. The product can be used on wrinkles, lines and creases Into the superficial and mid dermis

SALES GROWTH

Based on marketing data gathered for the years 2015 and 2016, where approx. 230.000 and 470.000 non-cross-linked HA products were sold respectively. Meanwhile, no adverse events were reported.

SAFETY PERFORMANCE

The post marketing clinical follow-up conducted for the year 2016 shows that out of the 54.000 patients treated, 79.2% reported a very significant improvement score, 13.2% reported a much improved score, 3.3%, reported an improved score and 0.13% reported no change.
The post marketing clinical follow-up conducted for the year 2015 shows that out of the 13.615 patients treated, 82.5% reported a very significant improvement score, 13.6% reported a much improved score, 3.8% reported an improved score while 0.1% reported an improved score. No unexpected adverse events were reported.

Based on existing marketing clinical follow-up data gathered from surgeons who have performed hundreds of thousands derma filler injections, during 2016.

Improvement Score on a Gais Scale

Based on existing marketing clinical follow-up data gathered from surgeons who have performed hundreds of thousands derma filler injections, during 2015.